Syllabus.pdf

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November 24, 2014
Syllabus MOOC TBP01x
Technology for Biobased Products
Learn the basics of process design for biobased products. From feedstock to biomaterials,
chemicals and biofuels.
A. Basic information
1. Introduction
Welcome to the MOOC Technology for Biobased Products. This syllabus describes the learning
objectives for the course, the content and explains the course grading system. Our MOOC lasts
6 weeks + 1 week to finish previous assignments. The course provides the insights and tools for
biotechnological processes design in a sustainable way. Five experienced course leaders will
teach you the basics of industrial biotechnology and how to apply these to the design of
fermentation processes for the production of biomaterials, chemicals and biofuels. We will also
introduce best practices in process design, from Brazil and the US, from academia and industry.
2. Learning Objectives
After this course you will:
1.
understand the need for sustainable innovation and how biobased production can
contribute to this;
2.
understand the global context of biobased production;
3.
be acquainted with the of biobased economy, from research to application and from
raw materials to products;
4.
have mastered the basics of industrial biotechnology;
5.
be able to integrate scientific and technological knowledge on the use of
bioprocesses for industrial products on the cell and process level;
6.
be capable of developing and assessing the conditions for efficient and sustainable
design of bioprocesses.
We know that some of you will simply audit the course because of time or other constraints.
Our web lectures and readings will indeed give you the basic understandings. However, we still
hope that you will join the discussions at any time. By collaboration with other students, by
sharing your own reflections and by completing the assignments, you - and your fellow
students! - will gain the most from this course.
3. Prerequisites
The prerequisites for this course are high school understanding of (bio)chemistry, biology and
mathematics. If you have a more advanced knowledge of these disciplines, we still expect that
the course will challenge you.
4. Course materials & workload
We will have a number of video lectures each week (8-10 minutes average) and corresponding
assignments. Each week, you will work on the ‘PDO-case’, in which you will design a process for
sustainable production of 1,3-propanediol. And we will explore other cases, so-called best
practices, presented by guest lecturers from academia and industry.
The expected workload throughout the course will be approximately 8 hours per week but this
will depend a lot on your ambitions and prior knowledge. The assignments and work on the
PDO-case also function to self-monitor your progress, which is indicated at the dashboard of the
course. For grading, see part C. You will have two weeks’ time to finish the assignments once
they are online. You can find the exact deadline dates in the navigation column under the
“Courseware” tab.
Communication will occur via the announcements, e-mail, and the discussion forum.
Announcements will mainly be used to address practical matters throughout the course and the
discussion forum should be used to discuss the content of the course. We invite you to use the
discussion forum actively!
Experience has shown us that the discussion forum can play a vital learning role in MOOCs.
Students can pose their questions or topics of discussion and other students can freely respond
to these topics. In this way you will also be able to help and learn from each other. The MOOC
team will monitor the discussion forum and on a weekly basis, the team will attempt to address
the main questions raised via weekly feedback videos.
For keeping track of where we are in describing and designing bioprocesses, the course provides
an animated overview of the whole bioprocess under the “animation” tab. At various stages you
can zoom in at will.
5. Networking and sharing knowledge
In this course we also count on your generosity. Become part of the network! Share your
thoughts and ideas. We have a few mechanisms in place:
A Twitter account: @TBP01x
Discussion forum. Here you can raise any questions on the content of the course and/or
seek collaboration with other students.
A world map. You can use the world map to introduce yourself (see tab ‘Map’ in the
navigation bar).
In many other MOOCs, students have set-up Facebook pages, Google hang-outs or
similar facilities. Please do feel encouraged to do the same.
B. Content of the course per week
Structure per week
Each week starts with a brief overview, followed by lectures interspersed with assignments.
Then, you will apply your gained knowledge in the weekly PDO case. The week is finished with a
best practice, which will give a glimpse at novel biotechnology and examples from the industry.
Terminology
In the course, you will probably encounter new words, symbols and equations. That is why we
have developed a terminology list as well as lists for symbols and equations used in the course.
One important word is used in two different meanings, ‘biomass’. In week 1, the term ‘biomass’
refers to feedstock, plant material used as a source for a fermentation production process. From
week 2, ‘biomass’ also refers to the cells of microorganisms in the fermenter.
Week 0: Introduction to the course
This week consists of:
A general introduction to the course and the lecturers;
An introduction to the course team;
A survey for you to tell us more about your background and expectations of the course.
Week 1: Biotechnology for Biobased Products
October 27, 2014
In this week, Isabel Arends and Patricia Osseweijer introduce you to the biobased economy.
They will show why our society should make the transition from fossil to biobased materials and
explain what the role of biotechnology is. They start from sustainable feedstocks and
microorganisms that can turn this biomass into valuable products. One of the products that can
be made through fermentation is 1,3-propanediol (PDO). It is a liquid that can be used as
building block for many different other products, such as polymers, coatings and solvents. Its
production will be the central case you will work on throughout all the weeks.
Lecture units
1.1
Why develop a biobased economy
1.2
Industrial biotechnology
1.3
Feedstocks - Renewable sources of biomass for biobased products
1.4
Process to bio-PDO (1,3-Propanediol)
1.5
Benefits for society & sustainability - Evaluating the effects of
biobased production

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